The Effect of Not Adding Proline Catalyst in the Enantiomeric Excess and Mosher’s Ester Configurational Analysis of Chiral Aldol (4-hydroxy-4-(2-nitrophenyl)butane-2-one)What would be the outcome of the reaction, if you would forget to add the proline catalyst? (Enantiomeric excess and Mosher’s ester configurational analysis of chiral aldol (4-hydroxy-4-(2-nitrophenyl)butane-2-one))

The Effect of Not Adding Proline Catalyst in the Enantiomeric Excess and Mosher’s Ester Configurational Analysis of Chiral Aldol (4-hydroxy-4-(2-nitrophenyl)butane-2-one)

The enantiomeric excess (EE) and Mosher’s ester configurational analysis of chiral aldol is used to determine the stereochemistry of a compound. It is important to add a proline catalyst when performing this reaction, as it can significantly affect the outcome. Without the proline catalyst, the reaction will not yield the desired results (Chen et al., 2019; Li et al., 2020).
Without the proline catalyst, the reaction may fail to reach the desired enantiomeric excess due to the lack of stereoselectivity (Li et al., 2020). Furthermore, the outcome of the Mosher’s ester configurational analysis may be incorrect due to the lack of an efficient catalyst (Chen et al., 2019). The proline catalyst helps in the efficient formation of the desired chiral aldol product (Chen et al., 2019). Without it, the reaction will not take place in the desired form and the desired results will not be obtained. The addition of a proline catalyst is essential in order to obtain the desired outcome in the enantiomeric excess and Mosher’s ester configurational analysis of chiral aldol. Without it, the reaction will not proceed in the desired form and the desired results will not be obtained. Therefore, it is important to ensure that the proline catalyst is added when performing these reactions. Cont…