Functional Groups Present in Doxepin
Doxepin is a tricyclic antidepressant drug used to treat depression, anxiety, and insomnia. It works by altering the amounts of certain chemicals in the brain, such as serotonin and norepinephrine. Doxepin is a synthetic compound that contains a number of distinct functional groups. These functional groups are responsible for the drug’s unique pharmacological properties and help to explain how it works (Horváth & Bíró, 2018). The most significant functional groups present in doxepin are an amine group, an amide group, an aromatic ring, and a dibenzoxepin ring. The amine group consists of a nitrogen atom bonded to two hydrocarbon substituents, which gives the molecule a basic character. The amide group, which consists of a nitrogen atom linked to a carbonyl group, is responsible for the drug’s biochemical activity. The aromatic ring, which consists of six carbon atoms bonded in a ring with alternating double and single bonds, makes the molecule more stable and less reactive. Lastly, the dibenzoxepin ring consists of two benzene rings connected by a six-member carbon-oxygen bridge (Goyal et al. 2019). This ring structure is thought to be the main component responsible for doxepin’s pharmacological effects. Cont…
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