Conversion of IMP to GMP: An Overview
The conversion of inosine monophosphate (IMP) to guanosine monophosphate (GMP) is an important biochemical reaction in the formation of the purine nucleotides pool. The reaction involves the enzymatic activity of IMP dehydrogenase (IMPDH) and GMP synthetase (GMPS). The two enzymes catalyze two distinct steps in the conversion of IMP to GMP. The first step involves the removal of a hydrogen atom from the IMP structure to form xanthylate, which is catalyzed by IMPDH. The reaction is as follows: IMP + NAD+ -> xanthylate + NADH + H+ (Fung et al., 2016). The second step is the addition of an amino group to the xanthylate structure, which is catalyzed by GMPS. The reaction is as follows: xanthylate + ATP + glutamine -> GMP + ADP + Pi + glutamate (Kumar et al., 2017). The conversion of IMP to GMP is an important part of the purine nucleotide cycle, which is essential for the regulation of cellular metabolism and energy production. The two enzymes involved in the conversion of IMP to GMP are important regulators of this cycle and play an important role in maintaining the balance of purine nucleotides in the cell. Cont….
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.Read more
Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.Read more
Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.Read more
Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.Read more
By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.Read more