Muscle phosphorylase kinase (M-PhK) is an enzyme found in the skeletal muscle cells. It catalyzes the transfer of phosphates from ATP to glycogen, thus playing a central role in energy metabolism and muscle contraction. A deficiency in M-PhK can lead to several symptoms including:
1. Muscle weakness: Patients with deficient M-PhK often experience fatigue and muscular weakness due to inefficient ATP production, resulting in inadequate energy for muscle contractions. This can also lead to difficulty performing activities that require sustained effort such as running or climbing stairs.
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