Explain the circumstances under which children should be prescribed drugs for off-label use.
First and foremost, any decision to prescribe drugs for off-label use should always be based on sound medical evidence. The provider should consider potential risks as well as benefits before making such a recommendation. Researching published peer-reviewed studies, consulting experts in the field, and considering clinical experience can help guide this process. Some conditions may benefit from an off-label drug without significant risk; however, there are also times when off-label prescribing can lead to serious adverse effects or even death if not done with caution. Thus, providers must assess individual cases carefully before deciding whether an off-label prescription is appropriate or beneficial for a child’s health care needs.
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