Events at the Synapse
Presynaptic Event: An action potential is generated in an axon by voltage-gated ion channels (VGCs). These VGCs open as a result of depolarization which causes an influx of sodium ions into the neuron, activating sodium-gated potassium channels (SGCs). The SGCs then open allowing potassium ions to leave the cell resulting in repolarization. This produces an action potential that propagates down the axon to reach its terminal boutons or synaptic knobs.
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