The Impact of a Carbohydrate Rich Dinner on Hepatic Metabolic Enzymes
It is well established that the intake of carbohydrates can have a significant impact on metabolic enzymes present in the liver. After consuming a carbohydrate-rich dinner, such as a pasta meal or a burger with a bun, the body will respond by releasing insulin from the pancreas. This insulin then binds to cell receptors and activates anabolic pathways in the liver, resulting in increased glycogenesis, lipogenesis, and cholesterol synthesis (Xu et al., 2016). At the same time, the insulin will also directly inhibit gluconeogenesis, fatty acid oxidation, and ketogenesis (Han et al., 2018).
Therefore, after consuming a carbohydrate-rich dinner, the metabolic enzymes likely to be activated in the liver are those involved in glycogenesis, lipogenesis, and cholesterol synthesis, while those likely to be inhibited are those involved in gluconeogenesis, fatty acid oxidation, and ketogenesis. This is the expected response to the introduction of carbohydrates into the body, and it serves to direct energy into the anabolic pathways that support the storage of glucose and lipids (Liu et al., 2019). Cont….
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