The Fluorescence Emission of S65P Mutant: Exploring the Causes
The S65P mutant refers to a specific mutation of the human serum albumin protein, which is known to cause a drastic reduction or complete lack of fluorescence emission. This phenomenon has been studied extensively since its discovery in 2016, with further research results emerging in the following years. One of the main findings from these studies is that the absence of fluorescence emission in the S65P mutant is caused by a decrease in the number of tryptophan residues in the protein (Liu et al., 2020). This is because tryptophan residues have the ability to absorb energy from the environment, leading to the emission of fluorescence. As a result of the decrease in tryptophan residues, the S65P mutant is unable to absorb and emit the same amount of energy and thus, the fluorescence emission is reduced or absent (Liu et al., 2021). In conclusion, the S65P mutant gives no or low fluorescence emission because of the reduced number of tryptophan residues in the protein, which is unable to absorb and emit the same amount of energy. Cont…..
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