In the beginning of fatty acid synthesis, acetyl ACP and malonyl ACP come together and form butyryl ACP in a series of four reactions. These reactions are repeated to add more carbons. What are these four reactions? Draw a simple structure for each step to show the product of this reaction. What coenzyme is required for two of these steps? The Four Reactions of Fatty Acid Synthesis and the Formation of Butyryl ACP

The 4 Reactions of Fatty Acid Synthesis and the Formation of Butyryl ACP

Fatty acid synthesis is a sequence of 4 reactions that begins with the mixture of acetyl ACP and malonyl ACP to kind butyryl ACP. These 4 reactions are the enoyl reductase response, the ketoacyl synthase response, the ketoacyl reductase response, and the acyl service protein (ACP) thioesterase response. The primary response is the enoyl reductase response, which is a dehydration response that mixes acetyl ACP and malonyl ACP to kind an acetoacetyl ACP. This response is catalyzed by the enzyme NADPH-dependent enoyl reductase (NADPH-ER).
The second response is the ketoacyl synthase response, which makes use of malonyl ACP so as to add a second carbon onto the acetoacetyl ACP. This response is catalyzed by the enzyme acetoacetyl-ACP synthase (AAS).
The third response is the ketoacyl reductase response, which reduces the ketone group of acetoacetyl ACP to an alcohol group. This response is catalyzed by the enzyme NADPH-dependent ketoacyl reductase (NADPH-KR). Cont….

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