Fill in the diagram about the fates of pyruvate. The Fate of Pyruvate: An Overview

The fate of Pyruvate: A review

Three-carbon acidic molecules, Pyruvate plays an important role in the metabolism and production of carbohydrates as well as fatty acids. This is the result of glycolysis (the first step of the glucose breakdown) and it can be used as a fuel for the citric acid cycle. Additionally, pyruvate may be transformed to other molecules depending on its metabolic needs. In cells, most pyruvate will be converted to acetyl–CoA and lactate. Gerland et. al. (2016). AcetylCoA is used to produce energy in the citric acid cycle, while anaerobic glucose is what produces lactate. If oxygen is present in the pyruvate, it can be oxidized and formed acetyl–CoA. This is used to create energy. If oxygen is lacking, pyruvate can be converted into lactate and then released from cells (Sahoo, 2019). Sometimes, pyruvate can form other molecules such as formate and ethanol. These molecules are essential for producing beer, wine and other alcoholic beverages (Gibson, 2021). You can convert pyruvate to alanine which is an important amino acid for protein synthesis. Cont….

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