Explain the ramifications to human metabolism and health of the liver lacking HFE protein. The Health Ramifications of the Liver Lacking HFE Protein

Lacking HFE Protein in the Liver Can Have a Health Impact

The liver plays a crucial role in human metabolism and is vital for our health. HFE protein is an essential component of liver function. A lack of HFE protein in the liver can have many health consequences, such as iron overload and inflammation. One of the most serious health effects of a liver deficient in HFE protein is iron overload. Iron overload is when the body has too much iron. This can lead to liver cirrhosis, joint pain, fatigue and diabetes. In 2018, a study showed that the lack of HFE protein caused iron overload (Jung and al., 2018).
The liver without HFE protein can also cause inflammation. This happens when your body’s natural defense mechanism is activated. According to Tian et. al. 2020 study, the lack of HFE protein from liver causes an increase in inflammatory marker (Tian 2020). Cont….

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